San Antonio de los Cobres, is located in Puna Salta, at a distance of 165 km from the city of Salta. At 3,774 meters, it is after El Aguilar and Mina Pirquitas, in Jujuy, the third highest town in Argentina. Gateway to the Salinas Grandes, the Puna and the La Polvorilla Viaduct of the Train to Las Nubes.
San Antonio de Los Cobres is located on National Route 40 and National Route 51 in Salta, Argentina